Paracetamol induced hepatic toxicity and amelioration by cinnamon in rats
نویسندگان
چکیده
منابع مشابه
Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats
BACKGROUND An overdose of paracetamol is a frequent reason for liver and renal toxicity and possible death and curcumin has hepatoprotective properties against liver damage. The exact mechanism of such protection is not clear. Therefore, this study was conducted to examine the molecular levels of the protective effect of curcumin on paracetamol overdose induced hepatic toxicity in rats. METHO...
متن کاملeffects of echinacea purpurea on hepatic and renal toxicity induced by diethylnitrosamine in rats
conclusions the current study findings indicated that echinacea purpurea extract played an important role in the protection against den toxicity in rats. results den induced hepatotoxicity and nephrotoxicity in all the treated animals by elevated serum alt, ast, alp and bun, creatinin and total and direct bilirubin levels. ast, bun and total and direct bilirubin significantly decreased in den +...
متن کاملHepato Protective and Antioxidant Role of Berberis tinctoria lesch Leaves on Paracetamol Induced Hepatic Damage in Rats
The scientific evaluation of medicinal plants used in the preparation of folk remedies has provided modern medicine with effective pharmaceuticals for the treatment of diseases. The methanol extract of Berberis tinctoria Lesch (Berberidaceae) leaves was investigated for its hepatoprotective and antioxidant effects on paracetamol (750 mg/kg) induced acute liver damage in Wistar albino rats. Hepa...
متن کاملCardiovascular baroreflex sensitivity attenuates by cisplatin-induced toxicity in rats
Introduction: Cisplatin (CP) therapy may disturb cardiovascular system control. The objective of this study was to find baroreflex sensitivity (BRS) in CP-induced nephrotoxicity in rats. Materials and Methods: Eighteen male and female Wistar rats were randomly assigned to two groups treated with CP (2.5 mg/kg/day) and the vehicle, for five consecutive days, and then were subjected to surgical ...
متن کاملAmelioration of carbon tetrachloride-induced hepatic injury by emulsified Antrodia extract
Objective(s): Antrodia cinnamomea (AC) is found with anti-inflammatory and immunomodulatory biological activities. In this study, we investigated the anti-hepatitis effect of the emulsified AC extract from RO water or supercritical fluid CO2 with ethanol co-solvent extract methods of AC preparations. Materials and Methods: Five groups of eight to ten weeks male rats with a count of ten for each...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Pharmacology and Toxicology
سال: 2016
ISSN: 2310-2985
DOI: 10.14419/ijpt.v4i2.6529